A NOVEL IL-5 AND IL-6 SENSITIVE PLASMACYTOMA CLONE, MD90
نویسندگان
چکیده
منابع مشابه
IL-6 transgenic mouse model for extraosseous plasmacytoma.
Plasma cell neoplasms in humans comprise plasma cell myeloma, otherwise known as multiple myeloma, Ig deposition and heavy chain diseases, and plasmacytoma (PCT). A subset of PCT, designated extramedullary PCT, is distinguished from multiple myeloma and solitary PCT of bone by its distribution among various tissue sites but not the bone marrow. Extramedullary (extraosseus) PCT are rare spontane...
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متن کاملHuman interleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: comparison and interaction with IL-1, IL-3, IL-6, and GMCSF.
Recombinant human interleukin-5 (rhIL-5), in either liquid or semi-solid cultures, selectively induced eosinophil production from normal human bone marrow, with no activity on other cell lineages. The time course of eosinophil production induced by murine IL-5, rhIL-3, and rh granulocyte-macrophage colony stimulating factor (GMCSF) was similar to rhIL-5. The rate of eosinophil maturation in vit...
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ژورنال
عنوان ژورنال: The KITAKANTO Medical Journal
سال: 1992
ISSN: 0023-1908,1883-6135
DOI: 10.2974/kmj1951.42.545